As criminals become more forensically aware of their traceability, forensic scientists need to up their game with advancing implementable technology. Technology improvements should aim to enhance recoverability of the evidence and expand, strengthen and communicate retrievable intelligence. Fingerprinting still remains one of the most powerful means of biometric identification. However it has been underplayed in terms of the additional value and information they contain. Pioneering work at Sheffield Hallam University, UK, has demonstrated the capabilities of Matrix Assisted Laser Desorption Ionisation Mass Spectrometry Imaging (MALDI MSI) to yield both physical and chemical information by providing multiple images of the same fingermark, simultaneous with additional intelligence. Physical information could complement the ridge pattern retrieved by CSI or even provide the only ridge pattern image for database comparison, as well as enabling separation of overlapping impressions. The opportunity to detect chemical information (small organic molecules, aminoacids, fatty acids, peptides, proteins and hence drugs, toiletry products, condom lubricants and blood as a few examples) could provide investigative leads on the physiological, pathological and lifestyle information as well as being useful to prove/disproof the suspect's statements. In recent publications, we also report on the opportunity to reliably detect and map the presence of blood onto the identifying ridges of a fingermark, thus providing associative evidence between the events of the bloodshed and the biometric information. Contextual consumption of drugs and alcohol can also be proved in police casework and this is useful to inform on the suspect's state of mind while committing the crime. Here, the pioneering use and rapid developments of MALDI MS based approaches for the analysis of latent and blood marks are presented together with insights into Police casework undertaken in collaboration with West Yorkshire Police, Defense Science and Technology Laboratory and the Home Office in UK.